The enzymatic deficiencies that are created can cause various abnormalities in the metabolism of proteins, lipids or carbohydrates (in their synthesis, assimilation, transport or degradation). They are managed through the lifelong maintenance of a restrictive diet.

However, the dietary manipulations required to manage these diseases may result in a deficiency of essential amino acids, fatty acids or micronutrients.

To prevent these deficiencies, special formulations for metabolic diseases are available that include both macronutrients and micronutrients while omitting the cause of the metabolic disorder and ensuring normal physical and mental development.